Bioengineering

This course examines the basic properties of biomaterials and methods so that students can manipulate them. Topics include the basic physiological consequences in relation to biomaterial implantation, and the methods for testing biomaterial compatibility. This course gives background knowledge for biomedical engineers to work in biomedical fields.

This course provides research training for exchange students. Students work on a research project under the guidance of assigned faculty members. Through a full-time commitment, students improve their research skills by participating in the different phases of research, including development of research plans, proposals, data analysis, and presentation of research results. A pass/no pass grade is assigned based a progress report, self-evaluation, midterm report, presentation, and final report.

This six-week summer course provides individual research training through the experience of belonging to a specific laboratory at Tohoku University. Students are assigned to a laboratory research group with Japanese and international students under the supervision of Tohoku University faculty. They participate in various group activities, including seminars, for the purpose of training in research methods and developing teamwork skills. The specific topic studied depends on the instructor in charge of the laboratory to which each student is assigned. The methods of assessment vary with the student's project and laboratory instructor. Students submit an abstract concerning the results of their individual research each semester and present the results near the end of this program.

The course equips students with an understanding of engineering approaches to advanced biomedical imaging. It strongly focuses understanding the physical processes that occur between a particular imaging modality and the biological material being investigated. This course introduces the physical concepts of advanced medical imaging via lectures focused on specific imaging modalities. Lectures cover various imaging techniques to provide an advanced understanding of the physics of the signal and its interaction with biological tissue; image formation or reconstruction; modality-specific issues for image quality; clinical applications; and biological effects and safety. This course uses state-of-the-art emerging imaging modalities in research and engineering approaches to advance such techniques to the clinic.  

This course gives an overview of contemporary approaches to tissue and cell engineering, including stem cells, cellular signaling, biomaterial scaffolds, use of bioreactors in tissue engineering, and controlled release strategies. Students explore ethical considerations related to clinical application of tissue and cell engineering technology. Topics include stem cells, embryogenesis, cellular signaling, extracellular matrix as a scaffold, degradable biomaterials for tissue engineering, cell-material interactions, scaffold design and fabrication, controlled drug release in tissue engineering, bioreactors in tissue engineering, production of mesenchymal stem cells, industrial tissue engineering manufacturing, cartilage tissue engineering, bone tissue engineering, cardiovascular tissue engineering, corneal tissue engineering and replacement, tissue engineering of the intervertebral disc (IVD). 

The course educates students in the area of medical device design. This is a broad course and its focus does not solely revolve around the engineering challenges associated with designing a medical device, lectures focus on many aspects: understanding clinical trial data, understanding the anatomical fundamentals associated with the device area, developing intellectual property strategies, regulation of medical devices, risk analysis, manufacturing techniques and requirements, reimbursement, and case studies of successful and unsuccessful medical device development.

This course explores materials used in tissue replacement including metallic, ceramic, and natural/synthetic polymeric materials. Implant applications and design considerations for these materials as well as the associated problems with long term survival are described so that the mechanical, chemical, and physiological interactions between in vivo host environment and the implanted biomaterial can be better understood. Integration of biomaterial structure and function are emphasized throughout the course. Advanced manufacturing and fabrication technologies to generate biomaterials with specialized structural and interfacial properties are introduced. Students obtain a detailed understanding of the composition and properties of the major classes of biomaterial used in medical devices. The required functionality for a range of synthetic implantable biomaterials and how this relates to material choice for specific applications are also covered. Associated failure modes are introduced through a series of real-life case studies. Sterilization techniques, regulatory aspects, and standards with relation to quality and safety are introduced. 

This course examines the essential areas in biomedical engineering, including technologies and applications in life sciences and medicine. The course is broadly divided into 4 areas: biomechanics and biomaterial; cell and tissue engineering; biomedical instrumentations and signals, and medical imaging. The global development and other issues, such as safety, ethics and industry will also be addressed.

This is a special studies course involving an internship with a corporate, public, governmental, or private organization, arranged with the Study Center Director or Liaison Officer. Specific internships vary each term and are described on a special study project form for each student. A substantial paper or series of reports is required. Units vary depending on the contact hours and method of assessment. The internship may be taken during one or more terms but the units cannot exceed a total of 12.0 for the year.